2mL serum (WTT). DO NOT use a serum separator tube
0.4mL serum (WTT)
Automated chemistry analyzer
Results available daily
(See test procedure section)
1mL serum (WTT); Do not submit in SST
Hemolysis, icterus, and SST gel
Nonloading Dose Treatment Protocol:
Measure bromide concentration one month into treatment and again at 2 to 3 months (steadystate concentration). 1 month bromide concentration approximates ½ of future steady state concentrations; Therefore, dose may be adjusted proactively.
Loading Dose Treatment Protocol:
1 month into treatment, and again in 23 months. If postloading and one month concentrations vary more than 10% from each other, maintenance dose can be modified accordingly.
Canine: 12.mg/mL (100200 mg/dl) in combination with Phenobarbital or 2.5 – 3.0 mg/mL (250300mg/dl) as sole anticonvulsant (without Phenobarbital) * Steadystate drug concentrations are expected in 34 months. Due to patient variability, therapeutic drug concentrations should be interpreted in combination with patient’s clinical signs. (Also see Phenobarbital)